McLaughlin Institute

Teresa M. Gunn, PhD

Associate Professor

teresa gunn

Laboratory Members

Postdoctoral Fellows
None at this time

Research Assistants
Derek Silvius



McGill University, BS, 1990, Biology

University of British Columbia, PhD, 1996, Genetics



1995-2001 Postdoctoral Fellow. Dr. Gregory Barsh, Stanford University, Palo Alto, CA

2001-2009 Assistant Professor. Department of Biomedical Sciences, Cornell University (Robert Hovey Udall Assistant Professor) Ithaca, NY

2009-present Associate Professor. McLaughlin Research Institute, Great Falls, MT


Major Areas of Research

The genetic and molecular basis of neurodegeneration, neuropathies and pigmentation.

gray tremor mouse neurodegeneration in gray

Gray tremor mouse

Neurodegeneration in gray termor mouse

Neurodegeneration in gray tremor mouse

Current Publications

Recent Journal Articles & Reviews

  • Walker WP, Oehler A, Edinger AL, Wagner KU, Gunn TM. (in press)
    Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform
    encephalopathy. Biol Cell 2016 Jul 13. doi: 10.1111/boc.201600014. PMID:
  • Anderson, SR, Lee, I, Ebeling, C, Stephenson, DA, Schweitzer, KM, Baxter, D,
    Moon, TM, LaPierre, S, Jaques, B, Silvius, D, Wegner, M, Hood, LE, Carlson, G,
    Gunn, TM (2015) Disrupted SOX10 function causes spongiform
    neurodegeneration in gray tremor mice. Mamm Genome 26(1-2):80-93. PMID:
  • Besio R, Maruelli S, Gioia R, Villa, I, Grabowski, P, Gallagher, O, Bishop, NJ,
    Foster, S, De Lorenzi, E, Colombo, R, Diaz, JL, Moore-Barton, H, Deshpande, C,
    Aydin, HI, Tokatli, A, Kwiek, B, Kasapkara, CS, Adisen, EO, Gurer, MA, Di
    Rocco, M, Phang, JM, Gunn, TM, Tenni, R, Rossi, A and Forlino, A (2015) Lack
    of prolidase causes a bone phenotype both in human and in mouse. Bone 72: 53-64.
    PMID: 25460580.
  • Gunn, TM and Carlson, GA (2013) RML prions act through Mahogunin and
    Attractin-independent pathways. Prion 7(4): 267-71. PMID: 23787699
  • Silvius, D, Pitstick, R, Ahn, M, Meishery, D, Oehler, A, Barsh, GS, DeArmond, SJ,
    Carlson, GA, Gunn, TM (2013) Levels of the Mahogunin Ring Finger 1 E3
    ubiquitin ligase do not influence prion disease. PLOS-One 8(1): e55575. PMID:
  • Gunn, TM, Silvius, D, Bagher, P, Sun, K, Walker, KK (2013) MGRN1-dependent
    pigment-type switching requires its ubiquitination activity but not its interaction
    with TSG101 or NEDD4. Pigment Cell Melanoma Res. 2013 26(2): 263-68. PMID:
  • Jesty, SA, Jung, SW, Cordeiro, JM, Gunn, TM, Di Diego, JM, Hemsley, S,
    Kornreich, BG, Hooker, G, Antzelevitch, C, Moïse, N (2013) Cardiomyocyte
    calcium cycling in a naturally occurring German shepherd dog model of inherited
    ventricular arrhythmia and sudden cardiac death. J Vet Cardiol. PMID: 23434243
  • Musser, MA, Munger, SC and Gunn, TM (2013) Meeting report of the 26th
    International Mammalian Genome Conference. Mamm Genome 24(5-6): 179-89.
    PMID: 23673682
  • Gunn, TM (2012) Functional annotation and ENU. BMC Res Notes, 5(1):580.
    PMID: 23095518
  • Gunn, TM (2011) Profile: Greg Barsh. Pigment Cell Melanoma Res 24(2):377.
  • Jung, SW, Silvius, D, Nolan, KA, Borchert, GL, Millet, YH, Phang, JM and Gunn,
    TM (2011) Developmental cardiac hypertrophy in a mouse model of prolidase
    deficiency. Birth Defects Res A Clin Mol Teratol., 91(4):204-17. PMID: 21472842
  • Friedenberg, SG, Zhu, L, Zhang, Z, Foels, WB, Schweitzer, PA, Wang, W, Fisher,
    PJ, Dykes, NL, Corey, E, Vernier-Singer, M, Jung, SW, Sheng, X, Hunter, LS,
    McDonough, SP, Lust, G, Bliss, SP, Krotscheck, U, Gunn, TM and Todhunter, RJ
    (2011) A Fibrillin-2 haplotype associated with canine hip dysplasia and incipient
    osteoarthritis. Am J Vet Res 72(4):530-40. PMID: 21453155
  • Brisban, A, Cruickshank, J, Moïse, NS, Gunn, T, Milano, A, Bustamante, CD and
    Mezey, JG (2011) Fast, Exact Linkage Analysis for Categorical Traits on Arbitrary
    Pedigree Designs. Genet Epidemiol, 35(5):371-80. PMID: 21520271
  • Walker, WP and Gunn, TM (2010) Piecing together the pigment-type switching
    puzzle. Pigment Cell Melanoma Res., 23(1):4-6. PMID: 20042018
  • Walker, WP and Gunn, TM (2010) Shades of meaning: the pigment-type
    switching system as a tool for discovery. Pigment Cell Melanoma Res., 23(4):485-

Book Chapters

  • Gunn, TM and Canine, B. Application of Mouse Genetics to Human Disease:
    Generation and Analysis of Mouse Models. In Roger Rosenberg and Juan Pascal
    (eds.), Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric
    Chapter 5, Fifth Edition. Waltham, MA: Academic Press, 2014.
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