McLaughlin Institute

Teresa M. Gunn, PhD

Associate Professor

Phone 406 454-6033
Email Teresa Gunn

teresa gunn


McGill University, BS, 1990, Biology
University of British Columbia, PhD, 1996, Genetics



1995-2001 Postdoctoral Fellowship, Stanford University, Palo Alto,CA
2001-2009 Assistant Professor, Dept of Biomedical Sciences, Cornell University, Ithaca, NY
2009-Present Associate Professor, McLaughlin Research Institute


Major Areas of Research

The genetic and molecular basis of neurodegeneration, neuropathies and pigmentation.

gray tremor mouse neurodegeneration in gray

Gray tremor mouse

Neurodegeneration in gray termor mouse

Neurodegeneration in gray tremor mouse

Current Publications

Selected Publications

Walker WP, Oehler A, Edinger AL, Wagner KU, Gunn TM. (in press)
Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform
encephalopathy. Biol Cell 2016 Jul 13. doi: 10.1111/boc.201600014. PMID:

Anderson, SR, Lee, I, Ebeling, C, Stephenson, DA, Schweitzer, KM, Baxter, D,
Moon, TM, LaPierre, S, Jaques, B, Silvius, D, Wegner, M, Hood, LE, Carlson, G,
Gunn, TM (2015) Disrupted SOX10 function causes spongiform
neurodegeneration in gray tremor mice. Mamm Genome 26(1-2):80-93. PMID:

Besio R, Maruelli S, Gioia R, Villa, I, Grabowski, P, Gallagher, O, Bishop, NJ,
Foster, S, De Lorenzi, E, Colombo, R, Diaz, JL, Moore-Barton, H, Deshpande, C,
Aydin, HI, Tokatli, A, Kwiek, B, Kasapkara, CS, Adisen, EO, Gurer, MA, Di
Rocco, M, Phang, JM, Gunn, TM, Tenni, R, Rossi, A and Forlino, A (2015) Lack
of prolidase causes a bone phenotype both in human and in mouse. Bone 72: 53-64.
PMID: 25460580.

Gunn, TM and Carlson, GA (2013) RML prions act through Mahogunin and
Attractin-independent pathways. Prion 7(4): 267-71. PMID: 23787699

Silvius, D, Pitstick, R, Ahn, M, Meishery, D, Oehler, A, Barsh, GS, DeArmond, SJ,
Carlson, GA, Gunn, TM (2013) Levels of the Mahogunin Ring Finger 1 E3
ubiquitin ligase do not influence prion disease. PLOS-One 8(1): e55575. PMID:

Gunn, TM, Silvius, D, Bagher, P, Sun, K, Walker, KK (2013) MGRN1-dependent
pigment-type switching requires its ubiquitination activity but not its interaction
with TSG101 or NEDD4. Pigment Cell Melanoma Res. 2013 26(2): 263-68. PMID:

Jesty, SA, Jung, SW, Cordeiro, JM, Gunn, TM, Di Diego, JM, Hemsley, S,
Kornreich, BG, Hooker, G, Antzelevitch, C, Moïse, N (2013) Cardiomyocyte
calcium cycling in a naturally occurring German shepherd dog model of inherited
ventricular arrhythmia and sudden cardiac death. J Vet Cardiol. PMID: 23434243

Musser, MA, Munger, SC and Gunn, TM (2013) Meeting report of the 26th
International Mammalian Genome Conference. Mamm Genome 24(5-6): 179-89.
PMID: 23673682

Gunn, TM (2012) Functional annotation and ENU. BMC Res Notes, 5(1):580.
PMID: 23095518

Gunn, TM (2011) Profile: Greg Barsh. Pigment Cell Melanoma Res 24(2):377.

Jung, SW, Silvius, D, Nolan, KA, Borchert, GL, Millet, YH, Phang, JM and Gunn,
TM (2011) Developmental cardiac hypertrophy in a mouse model of prolidase
deficiency. Birth Defects Res A Clin Mol Teratol., 91(4):204-17. PMID: 21472842

Friedenberg, SG, Zhu, L, Zhang, Z, Foels, WB, Schweitzer, PA, Wang, W, Fisher,
PJ, Dykes, NL, Corey, E, Vernier-Singer, M, Jung, SW, Sheng, X, Hunter, LS,
McDonough, SP, Lust, G, Bliss, SP, Krotscheck, U, Gunn, TM and Todhunter, RJ
(2011) A Fibrillin-2 haplotype associated with canine hip dysplasia and incipient
osteoarthritis. Am J Vet Res 72(4):530-40. PMID: 21453155

Brisban, A, Cruickshank, J, Moïse, NS, Gunn, T, Milano, A, Bustamante, CD and
Mezey, JG (2011) Fast, Exact Linkage Analysis for Categorical Traits on Arbitrary
Pedigree Designs. Genet Epidemiol, 35(5):371-80. PMID: 21520271

Walker, WP and Gunn, TM (2010) Piecing together the pigment-type switching
puzzle. Pigment Cell Melanoma Res., 23(1):4-6. PMID: 20042018

Walker, WP and Gunn, TM (2010) Shades of meaning: the pigment-type
switching system as a tool for discovery. Pigment Cell Melanoma Res., 23(4):485-

Book Chapters

Gunn, TM and Canine, B. Application of Mouse Genetics to Human Disease:
Generation and Analysis of Mouse Models. In Roger Rosenberg and Juan Pascal
(eds.), Rosenberg’s Molecular and Genetic Basis of Neurological and Psychiatric
Chapter 5, Fifth Edition. Waltham, MA: Academic Press, 2014.

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